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Antibodies

Anti-Bcl-2 (Apoptosis& Follicular Lymphoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:BCL2/2210R)

Product Sizes
20 µg
£408.00
12-1075-20UG
100 µg
£716.00
12-1075-100UG
About this Product
SKU:
12-1075
Additional Names:
Apoptosis regulator Bcl-2; B-cell CLL/lymphoma-2
translate.label.attr.clone:
BCL2/2210R
Clonality:
Monoclonal
Extra Details:
This antibody recognizes a protein of 25-26kDa; identified as the bcl-2lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression ofbcl-2lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas; neoplastic germinal centers express high levels of bcl-2lpha protein; whereas the normal or hyperplastic germinal centers are negative. Consequently; this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
Format:
Purified
Host:
Rabbit
Immunogen:
Recombinant full-length human bcl-2 protein
Isotype:
Rabbit IgG
Purification:
Protein A/G
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg