Anti-Bcl-2 (Apoptosis and Follicular Lymphoma Marker) Recombinant Mouse Monoclonal Antibody (Clone:rBCL2/796)
Product Sizes
20 µg
£408.00
12-1074-20UG
100 µg
£716.00
12-1074-100UG
About this Product
- SKU:
- 12-1074
- Additional Names:
- Apoptosis regulator Bcl-2; B-cell CLL/lymphoma-2
- translate.label.attr.clone:
- rBCL2/796
- Clonality:
- Monoclonal
- Extra Details:
- This antibody recognizes a protein of 25-26kDa; identified as the bcl-2 oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression ofbcl-2 oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas; neoplastic germinal centers express high levels of bcl-2 protein; whereas the normal or hyperplastic germinal centers are negative. Consequently; this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human bcl-2 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
