Anti-ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Recombinant Mouse Monoclonal Antibody (Clone:rCLIP/1407)
Product Sizes
20 µg
£408.00
12-1059-20UG
100 µg
£716.00
12-1059-100UG
About this Product
- SKU:
- 12-1059
- Additional Names:
- Adrenocorticotropin; alpha or beta or gamma Melanocyte Stimulating Hormone (MSH) or Melanotropin; beta-Endorphin; beta or gamma Lipotropin (LPH); CLIP; Met Enkephalin; POC; POMC
- translate.label.attr.clone:
- rCLIP/1407
- Clonality:
- Monoclonal
- Extra Details:
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes throµgh extensive; tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP; ACTH; alpha-MSH (Melanocyte Stimulating Hormone); beta-MSH; gamma-MSH; CLIP (corticotropin-like intermediary peptide); Lipotropin-beta; Lipotropin-gamma; beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells; B-cells; and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Synthetic peptide around aa 1-24 of human ACTH (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Protein A/G
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
