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Antibodies

Recombinant Rabbit Monoclonal Antibody to Caldesmon; HMW (h-Caldesmon) (Smooth Muscle Marker) (Clone : CALD1/1424R)

Product Sizes
20 µg
£408.00
12-1046-20UG
100 µg
£716.00
12-1046-100UG
About this Product
SKU:
12-1046
Additional Names:
CAD; CALD1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; CDM; HCAD; LCAD; NAG22
translate.label.attr.clone:
CALD1/1424R
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 150kDa; which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Format:
Purified
Immunogen:
Recombinant human full-length CALD1 protein
Isotype:
Rabbit IgG
Purification:
Purified Ab with BSA and Azide at 200ug/ml
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg