Recombinant Rabbit Monoclonal Antibody to TNF-alpha (Tumor Necrosis Factor alpha)(Clone : TNF/1500R)
Product Sizes
20 µg
£408.00
12-1042-20UG
100 µg
£716.00
12-1042-100UG
About this Product
- SKU:
- 12-1042
- Additional Names:
- APC1; Cachectin; Differentiation inducing factor (DIF); Macrophage cytotoxic factor (MCF); Necrosin; TNF alpha; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor
- translate.label.attr.clone:
- TNF/1500R
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes human 17-26kDa protein; which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17kDa free molecule; or as a 26kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages; and causes tumor necrosis when injected into tumor bearing mice. TNF alpha causes cytolysis of certain transformed cells; being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells; TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines; activating polymorphonuclear neutrophils and osteoclasts; and induction of interleukin 1; prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
- Format:
- Purified
- Immunogen:
- Recombinant full-length human TNF-alpha protein
- Isotype:
- Rabbit IgG
- Purification:
- Purified Ab with BSA and Azide at 200ug/ml
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
