Recombinant Rabbit Monoclonal Antibody to CD99 / MIC2 (Ewing s Sarcoma Marker)(Clone : MIC2/1495R)
Product Sizes
20 µg
£408.00
12-1031-20UG
100 µg
£716.00
12-1031-100UG
About this Product
- SKU:
- 12-1031
- Additional Names:
- 12E7; E2 antigen; MIC 2X; MIC 2Y; MIC2; Protein MIC2; Surface antigen MIC2; T-cell surface glycoprotein E2
- translate.label.attr.clone:
- MIC2/1495R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a sialoglycoprotein of 27-32kDa; identified as CD99; or MIC2 gene product; or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins; which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32). Although its function is not fully understood; CD99 is implicated in various cellular processes including homotypic aggregation of T cells; upregulation of T cell receptor and MHS molecules; apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes; cortical thymocytes; and granulosa cells of the ovary. Most pancreatic islet cells; Sertoli cells of the testis; and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.
- Format:
- Purified
- Immunogen:
- Recombinant human full-length MIC2 protein
- Isotype:
- Rabbit IgG
- Purification:
- Purified Ab with BSA and Azide at 200ug/ml
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
