Recombinant Rabbit Monoclonal Antibody to CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)(Clone : CFTR/1775R)
Product Sizes
20 µg
£408.00
12-1015-20UG
100 µg
£716.00
12-1015-100UG
About this Product
- SKU:
- 12-1015
- Additional Names:
- ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7); cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
- translate.label.attr.clone:
- CFTR/1775R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 165-170kDa; identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD); two nucleotide-binding domains (NBD); and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters; also known as traffic ATPases; which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3';5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas; airway; intestine; bile duct; sweat gland; and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
- Format:
- Purified
- Immunogen:
- Recombinant human CFTR fragment (aa258-385) (exact sequence is proprietary)
- Isotype:
- Rabbit IgG
- Purification:
- Purified Ab with BSA and Azide at 200ug/ml
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
