Recombinant Mouse Monoclonal Antibody to Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker)(Clone : rWT1/857)
Product Sizes
20 µg
£408.00
12-1011-20UG
100 µg
£716.00
12-1011-100UG
About this Product
- SKU:
- 12-1011
- Additional Names:
- WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
- translate.label.attr.clone:
- rWT1/857
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 47-55kDa-tumor suppressor protein; identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids; frequently found in subsets of sporadic Wilm s tumors. WT1; a sporadic and familial pediatric kidney tumor; is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1; a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium; and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells; malignant mesothelioma; ovarian carcinoma; gonadoblastoma; nephroblastoma; and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- Format:
- Purified
- Immunogen:
- Recombinant full-length human WT1 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Purified Ab with BSA and Azide at 200ug/ml
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
