Polyclonal Antibody to Spi-B
Product Sizes
25ug
£319.00
11-8052-25UG
100ug
£407.00
11-8052-100UG
About this Product
- SKU:
- 11-8052
- Additional Names:
- SPIB
- Clonality:
- Polyclonal
- Extra Details:
- Spi-B belongs to the ETS family transcription containing a conserved ETS domain which specifically binds to a purine-rich DNA sequence called the PU-box (5'-GAGGAA-3'). Spi-B has two known isoforms (28 and 18 kDa) localized in nucleus and cytoplasm. Spi-B contains two transactivation domains (TAD) at the N- terminal end which may be required for transcriptional activation of the target genes. Spi-B is involved in development of plasmacytoid dendritic cells (natural interferon producing cells) and B-cell development. Spi-B acts as a lymphoid specific enhancer. Spi-B is highly expressed in plasmacytoid dendritic cells (pDCs), B-cells and stem cell populations of the liver.
- Format:
- Purified
- Gene Details:
- SPIB
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant Spi-B protein (amino acids 50-260) was used as the immunogen for this antibody.
- Isotype:
- Rabbit IgG
- Purification:
- Protein A Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
