Polyclonal Antibody to PACS-1
Product Sizes
25ug
£319.00
11-8005-25UG
100ug
£407.00
11-8005-100UG
About this Product
- SKU:
- 11-8005
- Additional Names:
- PACS1||KIAA1175
- Clonality:
- Polyclonal
- Extra Details:
- PACS1 or phosphofurin acidic cluster sorting protein 1 belongs to the PACS familyof proteins and is involved in protein trafficking. PACS1 contains an acidic cluster sorting motifs and plays an important role in the localization of trans-Golgi network (TGN) membrane proteins. It has also been implicated in secretory granule biogenesis. In order to enable HIV-1 to escape immune surveillance, PACS-1 is also reported to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the trans-golgi network. Diseases caused by mutation in this gene include mental retardation (MRD17) and AIDS. PACS1 has expression in adipose tissue, liver, spleen, bone, blood, brain. It has 2 isoforms produced by alternative splicing.
- Format:
- Purified
- Gene Details:
- PACS1
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant PACS-1 protein (amino acids 150-400) was used as the immunogen for this antibody.
- Isotype:
- Rabbit IgG
- Purification:
- Protein A Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
