Polyclonal Antibody to BRD4, HUNK1
Product Sizes
25ug
£319.00
11-7501-25UG
100ug
£407.00
11-7501-100UG
About this Product
- SKU:
- 11-7501
- Additional Names:
- BRD4||HUNK1
- Clonality:
- Polyclonal
- Extra Details:
- BRD4 is a member of the BET (bromo domain and extra terminal domain) family, along with BRD2, BRD3 and BRDT. BRD4 is required to form the transcriptionally active P-TEFb complex by displacing negative regulators such as HEXIM1 and 7SKsnRNA complex from P-TEFb, thereby transforming it into an active form that can then phosphorylate the C-terminal domain (CTD) of RNA polymerase II. A chromosomal aberration involving BRD4 is found in a rare, aggressive and lethal carcinoma arising in midline organs of young people. It expressed ubiquitously and has three isoforms. Isoform B acts as a chromatin insulator in the DNA damage response pathway.
- Format:
- Purified
- Gene Details:
- BRD4
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant BRD4 protein (amino acids 140-500) was used as the immunogen for this antibody.
- Isotype:
- Rabbit IgG
- Purification:
- Protein A Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
