Polyclonal Antibody to DLL4
Product Sizes
25ug
£319.00
11-10033-25UG
100ug
£407.00
11-10033-100UG
About this Product
- SKU:
- 11-10033
- Additional Names:
- DLL4||UNQ1895/PRO4341
- Clonality:
- Polyclonal
- Extra Details:
- Dll4 (Delta-like 4), a membrane-bound Notch ligand, plays a fundamental role in vascular development and angiogenesis. It is highly expressed in capillary endothelial tip cells and is involved in suppressing neighboring stalk cells to become tip cells during angiogenesis. Dll4-Notch signaling is mediated either by direct cell-cell contact or by Dll4-containing exosomes from a distance. DLL4 signaling is extensively critical for tumor angiogenesis. Blockage of DLL4 signaling inhibits tumor growth by deregulating angiogenesis and promoting non productive angiogenesis. Additionally, DLL4 has been shown to help regulate the cellular actions of VEGF.
- Format:
- Purified
- Gene Details:
- DLL4
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant DLL4 protein (amino acids 423-650) was used as the immunogen for this antibody.
- Isotype:
- Rabbit IgG
- Purification:
- Protein A Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
