Monoclonal Antibody to MITF (Clone: ABM1H91)
Product Sizes
25ug
£319.00
10-8004-25UG
100ug
£429.00
10-8004-100UG
About this Product
- SKU:
- 10-8004
- Additional Names:
- MITF||BHLHE32
- translate.label.attr.clone:
- ABM1H91
- Clonality:
- Monoclonal
- Extra Details:
- MITF (Microphthalmia-associated transcription factor) is a basic helix-loop-helix leucine zipper (bHLH-Zip) family factor, involved in lineage-specific pathway regulation of many types of cells including osteoclasts, melanocytes, retinal pigment epithelial cells, mast cells and natural killer cells. It plays a critical role in melanogenesis as a transcriptional activator of tyrosinase, TRP-1, and TRP-2. Moreover, it regulates specification, survival, and proliferation of normal melanocytes, and controls proliferation, migration and invasion of melanoma cells. MITF is the most characterized member of the MIT family, mutations of which can lead to diseases such as Melanoma, Waardenburg syndrome, and Tietz syndrome.
- Format:
- Purified
- Gene Details:
- MITF
- Host:
- Mouse
- Immunogen:
- A partial length recombinant MITF protein (amino acids 150-427) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG1 Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
