Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42)
Product Sizes
25ug
£319.00
10-7612-25UG
100ug
£429.00
10-7612-100UG
About this Product
- SKU:
- 10-7612
- Additional Names:
- Programmed cell death protein 1; Protein PD-1; CD279
- translate.label.attr.clone:
- ABM5F42
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Extra Details:
- PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
- Format:
- Purified
- Gene Details:
- Pdcd1
- Host:
- Rat
- Immunogen:
- partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody.
- Isotype:
- Rat IgG2b, kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
