Monoclonal Antibody to PAPP-A (Clone: ABM4C62)
Product Sizes
25ug
£319.00
10-7569-25UG
100ug
£429.00
10-7569-100UG
About this Product
- SKU:
- 10-7569
- Additional Names:
- Insulin-like growth factor-dependent IGF-binding protein 4 protease; IGF-dependent IGFBP-4 proteas; Pregnancy-associated plasma protein A
- translate.label.attr.clone:
- ABM4C62
- Clonality:
- Monoclonal
- Extra Details:
- PAPP-A (pregnancy-associated plasma protein A) is a zinc metalloproteinase in the insulin-like growth factor system that is expressed by tissues outside of pregnancy and involved in normal and dysregulated growth. It has prognostic impact in pregnancy and acute coronary syndrome. PAPP-A regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. PAPP-A levels is associated with abnormal glucose metabolism and increased risk of atherosclerosis in AGHD (Adult Growth Hormone Deficiency) patients.
- Format:
- Purified
- Gene Details:
- PAPPA
- Host:
- Mouse
- Immunogen:
- A partial length recombinant PAPP-A protein (amino acids 332-561) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2b Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
