Monoclonal Antibody to CD11c (Clone: ABM4C58)
Product Sizes
25ug
£319.00
10-7566-25UG
100ug
£429.00
10-7566-100UG
About this Product
- SKU:
- 10-7566
- Additional Names:
- ITGAX||CD11C
- translate.label.attr.clone:
- ABM4C58
- Clonality:
- Monoclonal
- Extra Details:
- CD11c/CD18 ( p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages.
- Format:
- Purified
- Gene Details:
- ITGAX
- Host:
- Mouse
- Immunogen:
- A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2b Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:FLOW1.jpg
