Monoclonal Antibody to FLT1 (Clone: ABM4A56)
Product Sizes
25ug
£319.00
10-7564-25UG
100ug
£429.00
10-7564-100UG
About this Product
- SKU:
- 10-7564
- Additional Names:
- FLT1||FLT||FRT||VEGFR1
- translate.label.attr.clone:
- ABM4A56
- Clonality:
- Monoclonal
- Extra Details:
- FLT-1 (fms-related tyrosine kinase 1) is an endogenous inhibitor of vascular endothelial growth factor, which is involved in cardiovascular remodeling and atherosclerosis development. It potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). FLT-1 is expressed on tumor cells and is implicated in tumor growth and progression. It is overexpressed in primary tumors and nodal metastasis. FLT-1 regulates monocyte migration, recruits endothelial cell progenitors, increases the adhesive properties of natural killer cells and induces growth factors. It is observed in many diseases with endothelial dysfunction, including pre-eclampsia and diabetic retinopathy, but whether it contributes to endothelial injury in IgAN requires further exploration.
- Format:
- Purified
- Gene Details:
- FLT1
- Host:
- Mouse
- Immunogen:
- A partial length recombinant FLT1 protein (amino acids 102-321) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2b Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
