Monoclonal Antibody to c-erbB-2/Her2 (Clone: ABM45F5)
Product Sizes
25ug
£319.00
10-7563-25UG
100ug
£429.00
10-7563-100UG
About this Product
- SKU:
- 10-7563
- Additional Names:
- ERBB2||HER2||MLN19||NEU||NGL
- translate.label.attr.clone:
- ABM45F5
- Clonality:
- Monoclonal
- Extra Details:
- HER2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12), encoding a type 1 tyrosine kinase growth factor receptor and the role of HER2 in the development of numerous types of human cancer. HER2 is a transmembrane receptor comprising an extracellular domain (ECD), a single transmembrane domain, and an intracellular domain (ICD) with tyrosine-kinase activity.The high-expression and amplification of C-erbB-2 and its protein products (P185) are found in a wide variety of tumors. HER2 is overexpressed in 10% to 35% of gastric and gastroesophageal junction (GEJ) adenocarcinomas.
- Format:
- Purified
- Gene Details:
- ERBB2
- Host:
- Mouse
- Immunogen:
- A partial length protein (amino acids 301-522) was used as the immunogen for this antibody (from extra cellular domain of c-erbB-2).
- Isotype:
- Mouse IgG2b Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
