Monoclonal Antibody to Human PD-L1 (Clone: ABM4E54) (BSA/AZIDE Free)
Product Sizes
25ug
£319.00
10-7562-BAF-25UG
100ug
£429.00
10-7562-BAF-100UG
About this Product
- SKU:
- 10-7562-BAF
- Additional Names:
- CD274||B7H1||PDCD1L1||PDCD1LG1||PDL1
- translate.label.attr.clone:
- ABM4E54
- Clonality:
- Monoclonal
- Extra Details:
- PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belonging to the B7 superfamily that inhibits immune responses through its receptor, PD-1. PD-L1 plays a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells, and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells, and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation, and in numerous autoimmune diseases.
- Format:
- Purified
- Gene Details:
- CD274
- Host:
- Mouse
- Immunogen:
- A partial length recombinant PDL1 protein (amino acids 18-227) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2a Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:FLOW1.jpg
