Monoclonal Antibody to CDC25A (Clone: ABM4A46)
Product Sizes
25ug
£319.00
10-7554-25UG
100ug
£429.00
10-7554-100UG
About this Product
- SKU:
- 10-7554
- Additional Names:
- CDC25A
- translate.label.attr.clone:
- ABM4A46
- Clonality:
- Monoclonal
- Extra Details:
- CDC25A is a dual specificity (tyr/thr) phosphatase and a putative upregulated c-Myc target gene. It is a regulator of the cell cycle required for progression from G1 to S phase. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. Overexpression of CDC25A bypassed the mechanism of cell cycle arrest, leading to enhanced DNA damage and decreased cell survival. Specific degradation of CDC25A is identified as part of the DNA damage checkpoint mechanism and suggested how CDC25A overexpression in human cancers might contribute to tumorigenesis.
- Format:
- Purified
- Gene Details:
- CDC25A
- Host:
- Mouse
- Immunogen:
- A partial length recombinant CDC25A protein (amino acids 190-484) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2b Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
