Monoclonal Antibody to E-cadherin (Clone: ABM43F8)
Product Sizes
25ug
£319.00
10-7546-25UG
100ug
£429.00
10-7546-100UG
About this Product
- SKU:
- 10-7546
- Additional Names:
- CDH1||CDHE||UVO
- translate.label.attr.clone:
- ABM43F8
- Clonality:
- Monoclonal
- Extra Details:
- Epithelial cadherin (E-cadherin) is a calcium dependent cell-cell adhesion glycoprotein. It is associated with gland formation, stratification, and epithelial polarization. Its deregulation affects cell-cell adhesion and results in increased invasiveness of distinct human carcinomas like gastric cancer, malignancy, oral squamous cell carcinoma, Atypical parathyroid adenoma (APA). Loss of function of E-cadherin leads to the disappearance of epithelial characteristics of the cells and generates higher invasiveness for extracellular matrices. E-cadherin expression is considered to be a decisive indicator for differentiation, aggressive behaviour, high proliferation, metastasis, poor prognosis and invasiveness of human carcinoma cells.
- Format:
- Purified
- Gene Details:
- CDH1
- Host:
- Mouse
- Immunogen:
- A partial length recombinant E-cadherin protein (amino acids 438-556) was used as the immunogen for this antibody .
- Isotype:
- Mouse IgG1 Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
