Monoclonal Antibody to ALK-1 (Clone: ABM43C4)
Product Sizes
25ug
£319.00
10-7542-25UG
100ug
£429.00
10-7542-100UG
About this Product
- SKU:
- 10-7542
- Additional Names:
- ACVRL1||ACVRLK1||ALK1
- translate.label.attr.clone:
- ABM43C4
- Clonality:
- Monoclonal
- Extra Details:
- ALK-1 or Activin receptor-like kinase-1 is a type I cell surface receptor for the TGF-beta (transforming growth factor-beta) super family of proteins. It is expressed predominantly in endothelial cells with moderate expression in smooth muscle cells, myofibroblast, hepatic stellate cells, chondrocytes, monocytes, myoblasts, macrophages and fibroblasts. ALK-1 plays a pivotal role in vascular remodelling and angiogenesis. More specifically its key function is in arterial/venous differentiation during embryonic vascular development. Mutations in ALK-1 gene (12q11-14) causes HHT2 (Hereditary Haemorrhagic Telangiectasia type 2), an autosomal dominant multisystem vascular dysplasia caused by a haploinsufficiency mechanism.
- Format:
- Purified
- Gene Details:
- ACVRL1
- Host:
- Mouse
- Immunogen:
- A partial length recombinant ALK-1 protein (amino acids 310-503) was used as the immunogen for this antibody
- Isotype:
- Mouse IgG1 Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
