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Antibodies

Monoclonal antibody to CD16 (Clone: B73.1) No Azide, Low Endotoxin

Product Sizes
100ug
£429.00
10-4206-NALE-100UG
About this Product
SKU:
10-4206-NALE
Additional Names:
CD16-II; CD16a antigen; Fc-gamma RIII-alpha; FcR-10; IgG Fc receptor III-2; CD16A; FCG3; FCGR3; IGFR3
Application:
Immunofluorescence
translate.label.attr.clone:
B73.1
Clonality:
Monoclonal
Extra Details:
CD16, also known as low affinity IgG receptor III (FcgammaRIII), is expressed as two distinct forms, referred to as CD16a and CD16b. CD16a (FcgammaRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells, and placental trophoblasts in humans. CD16b (FcgammaRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein whose extracellular domain is over 95% homologous to that of CD16a, and is expressed specifically on neutrophils. CD16 binds to aggregated IgG or IgG-antigen complex, which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Format:
Purified
Gene Details:
FCGR3A
Host:
Mouse
Immunogen:
NK cell-enriched fraction from human peripheral blood was used as the immunogen for this antibody.
Isotype:
Mouse IgG1k
Purification:
Protein G Chromatography
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody