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Antibodies

Monoclonal Antibody to Rat NKp46 (Clone: WEN23)

Product Sizes
25ug
£319.00
10-4194-25UG
100ug
£429.00
10-4194-100UG
About this Product
SKU:
10-4194
Additional Names:
Natural cytotoxicity triggering receptor 1; Activating receptor 1; Lymphocyte antigen 94 homolog; NK receptor KILR-1; Natural killer cell p46-related protein; CD335
translate.label.attr.clone:
WEN23
Clonality:
Monoclonal
Conjugate:
Unconjugated
Extra Details:
Rat NKp46 is an activating receptor expressed on all NK cells in all rat strains tested. NKp46 is the defining surface marker for rat NK cells. No expression of NKp46 has so far been reported on non-NK cells in the rat. NKp46 associates with the activating adaptor proteins FcepsilonRIgamma and CD3zeta and activates NK cell cytotoxicity and IFNgamma production.
Format:
Purified
Gene Details:
Ncr1
Host:
Mouse
Immunogen:
Recombinant rat NKp46 ectodomain coupled to the Fc portion of mouse IgG2b was used as the immunogen for this antibody.
Isotype:
Mouse IgG1, Kappa
Purification:
Protein G Chromatography
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure-1: Cell surface staining of rat splenocytes. Green represents isotype control; red represents anti-rat NKP46 (10-4194) antibody. 0.2 µg antibody was used. Goat anti-mouse FITC was used as secondary antibody.
Figure-1: Cell surface staining of rat splenocytes. Green represents isotype control; red represents anti-rat NKP46 (10-4194) antibody. 0.2 µg antibody was used. Goat anti-mouse FITC was used as secondary antibody.
Figure-2: Flow cytometry analysis of anti-NKp46 (Cat.No.: 10-4194) in IL-2-stimulated Rat NK cells. Black line represent anti-NKp46 (Clone:WEN23); dotted line represent Secondary antibody control.
Figure-3: Western blot analysis of anti-NKp46 in 293T cells transfected with a rat NKp46 expression construct and empty vector (EV) lysates at Non-reducing (NR) and reducing (R) condition.