Monoclonal Antibody to IL-36R (Clone: ABM4B73)
Product Sizes
25ug
£319.00
10-4167-25UG
100ug
£429.00
10-4167-100UG
About this Product
- SKU:
- 10-4167
- Additional Names:
- IL1RL2||IL1RRP2
- translate.label.attr.clone:
- ABM4B73
- Clonality:
- Monoclonal
- Extra Details:
- IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1 Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.
- Format:
- Purified
- Gene Details:
- IL1RL2
- Host:
- Mouse
- Immunogen:
- A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2b, kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
