Monoclonal Antibody to MUL1 (Clone: ABM4F71)
Product Sizes
25ug
£319.00
10-4165-25UG
100ug
£429.00
10-4165-100UG
About this Product
- SKU:
- 10-4165
- Additional Names:
- MUL1||C1orf166||GIDE||MAPL||MULAN||RNF218
- translate.label.attr.clone:
- ABM4F71
- Clonality:
- Monoclonal
- Extra Details:
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
- Format:
- Purified
- Gene Details:
- MUL1
- Host:
- Mouse
- Immunogen:
- A partial length recombinant MUL1 protein (amino acids 146-352) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG1, kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
