Monoclonal Antibody to CD20 (Clone: ABM46C7) FITC Conjugated
Product Sizes
25ug
£319.00
10-4162-F-25UG
100ug
£375.00
10-4162-F-100UG
About this Product
- SKU:
- 10-4162-F
- Additional Names:
- MS4A1||CD20
- translate.label.attr.clone:
- ABM46C7
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- CD20 is clinically validated as an immunotherapy target for B-cell lymphomas and autoimmune diseases. CD20 consists of large, intracellular, amino- and carboxyterminal portions connected by 4 membrane-spanning domains. Its high expression on malignant B cells and its reported lack of shedding from the surfacemake CD20 an ideal target for antibody-mediated killing. Anti-CD20 antibodies are believed to mediate the therapeutic effect by activation of complement-dependent cytotoxicity (CDC) and largely by antibody-dependent cellular cytotoxicity exerted by recruitment of innate immune effector cells expressing the Fcgamma receptor IIIa.
- Format:
- Purified
- Gene Details:
- MS4A1
- Host:
- Mouse
- Immunogen:
- A partial length recombinant protein corresponding to extra cellular domain of CD20 was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2b Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:10-4162-F.jpg
