Monoclonal Antibody to mCD11c (Clone: ABM-N418)
Product Sizes
25 µg
£204.00
10-4124-25UG
About this Product
- SKU:
- 10-4124
- Additional Names:
- CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150;95 alpha chain; Leukocyte adhesion receptor p150;95; Integrin alpha-X
- translate.label.attr.clone:
- ABM-N418
- Clonality:
- Monoclonal
- Extra Details:
- CD11c/CD18 ( p150/95; or complement receptor 4; CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS; ICAM-1; ICAM-2; ICAM-4 and VCAM-1); extracellular matrix proteins (collagen I); and soluble ligands (iC3b; heparin and fibrinogen). It is expressed in macrophages; monocytes; granulocytes; subsets of T and B cells; and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells; where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages.
- Format:
- Purified
- Host:
- Hamster
- Isotype:
- Hamster IgG
- Purification:
- Protein G Chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
