Monoclonal Antibody to CD73 (Clone: ABM40E2)
Product Sizes
25ug
£319.00
10-4106-25UG
100ug
£429.00
10-4106-100UG
About this Product
- SKU:
- 10-4106
- Additional Names:
- NT5E||NT5||NTE
- translate.label.attr.clone:
- ABM40E2
- Clonality:
- Monoclonal
- Extra Details:
- CD73, also known as ecto-5'-nucleotidase, is a glycosyl-phosphatidylinositol linked plasma membrane glycoprotein that is expressed on multiple cell types and in different tissues. It is a key enzyme in the regulation of purinergic signaling and inflammatory reactions. It hydrolyzes extracellular AMP into adenosine, which dampens immune cell activation, and reduces leukocyte trafficking CD73 potently suppresses antitumor T cell responses through its ability to generate adenosine. It has also emerged as an important regulator of tissue homeostasis and pathophysiologic responses related to immunity, inflammation, pain, ischemia, tissue fibrosis and cancer.
- Format:
- Purified
- Gene Details:
- NT5E
- Host:
- Mouse
- Immunogen:
- A partial length recombinant CD73 protein (amino acids 145-346) was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG2a Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:IHC.jpg
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