Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Monoclonal Antibody to RIG-I (Clone: ABM40B5)

Product Sizes
25ug
£319.00
10-4102-25UG
100ug
£429.00
10-4102-100UG
About this Product
SKU:
10-4102
Additional Names:
DDX58
translate.label.attr.clone:
ABM40B5
Clonality:
Monoclonal
Extra Details:
RIG-I or Probable ATP-dependent RNA helicase DDX58 or simply DDX58 is a RNA helicase enzyme with two isoforms (106 and 101 kDa). RIG-I belongs to the DEAD/H box family and is involved in several cellular responses including RNA binding and alteration of RNA secondary structure. RIG-1 acts as sensor of viral nucleic acids thus activating a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines. Generally it remains as a monomer but upon activation by viral dsRNA it homomultimerizes and interacts with mitochondria antiviral signaling protein (MAVS/IPS1) which activating a cascade of reactions to produce specific interferon. RIG-1 is mostly expressed in vascular smooth cells.
Format:
Purified
Gene Details:
DDX58
Host:
Mouse
Immunogen:
A partial length recombinant human RIG-I protein (amino acids 1-220) was used as the immunogen for this antibody.
Isotype:
Mouse IgG1 Kappa
Purification:
Protein G Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig-2 : Immunohistochemical analysis of RIG-I in human prostate tissue using RIG-I antibody (Clone: ABM40B5) at 5 µg/ml.
Figure-3: Intracellular flow cytometric analysis of RIG-I in K562 Cell line using 0.5 µg/10^6 cells of Anti-RIGI antibody (ABM40B5). Green represent isotype control and red represent Anti-RIG I antibody (10-4102 Abeomics). Goat anti-mouse PE conjugate was used as secondary.
Figure-3: Intracellular flow cytometric analysis of RIG-I in K562 Cell line using 0.5 µg/10^6 cells of Anti-RIGI antibody (ABM40B5). Green represent isotype control and red represent Anti-RIG I antibody (10-4102 Abeomics). Goat anti-mouse PE conjugate was used as secondary.