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Antibodies

Monoclonal Antibody to CD33(Clone: ABM29D3)

Product Sizes
25ug
£319.00
10-4064-25UG
100ug
£375.00
10-4064-100UG
About this Product
SKU:
10-4064
Additional Names:
CD33||SIGLEC3
translate.label.attr.clone:
ABM29D3
Clonality:
Monoclonal
Extra Details:
CD33 is a member of the SIGLEC (Sialic Acid-Binding Ig-Like Lectin) family of receptors, and the gene comprises seven coding exons. Exon 2 encodes the canonical IgV domain, exon 4 encodes the IgC structural domain, and exons 6 and 7 encode cytosolic ITIMs (Immunotyrosine Inhibitory Motifs). CD33 acts as a cell surface antigen which is expressed on normal myeloid cells and CD34+ blasts in AML (Acute Myeloid Leukemia). The antigen serves as a target of GO (Gemtuzumab/Ozogamicin), which exerts anti-leukemic effects in refractory AML.
Format:
Purified
Gene Details:
CD33
Host:
Mouse
Immunogen:
A partial length recombinant CD33 protein (amino acids 28-320) was used as the immunogen for this antibody.
Isotype:
Mouse IgG2a Kappa
Purification:
Protein G Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Fig-2: Western blot analysis of CD33. Anti- CD33 antibody (Clone: ABM29D3) was used at 2 µg/ml on Human Spleen and DU145 lysates.
Fig-3: Immunohistochemical analysis of CD33 in Renal Cell Carcinoma using CD33 antibody (Clone: ABM29D3) at 5 µg/ml.
Fig-4: Immunohistochemical analysis of CD33 in squamous cell carcinoma of esophagus using CD33 antibody (Clone: ABM29D3) at 5 µg/ml.
Fig-4: Immunohistochemical analysis of CD33 in squamous cell carcinoma of esophagus using CD33 antibody (Clone: ABM29D3) at 5 µg/ml.
Fig-5: Cell Surface flow analysis of hCD33 in PBMC (Monocytes) using 0.2µg/10^6 cells of CD33 clone ( ABM29D3). Green represents isotype control; red represents anti-hCD33 antibody. Goat anti-mouse PE conjugated secondary antibody (ABEOMICS) was used.