Recombinant anti-human-IL-1 beta Antibody (Canakinumab)
Product Sizes
50µg
£518.00
10-2003-50UG
About this Product
- SKU:
- 10-2003
- Additional Names:
- Interleukin-1 beta; Catabolin
- Clonality:
- Monoclonal
- Extra Details:
- Target: IL-1 Beta Generic name: Canakinumab Product Origin: Recombinant in CHO cells Canakinumab is a recombinant; human anti-human-IL-1betamonoclonal antibody that belongs to the IgG1/kappa isotype subclass with a molecular mass of 145157 Daltons when deglycosylated. Canakinumab binds to human IL-1betaand neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors; but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra). References: 1. Church LD; McDermott MF: Canakinumab; a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders. Curr Opin Mol Ther. 2009 Feb;11(1):81-89. 2. Lachmann HJ; et al.: Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med. 2009 Jun 4;360(23):2416-25. doi:10.1056/NEJMoa0810787
- Format:
- Purified
- Purification:
- Purity: >98.0% as determined by SEC-HPLC & SDS-PAGE.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
