Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)
Product Sizes
25ug
£319.00
10-1058-25UG
100ug
£429.00
10-1058-100UG
About this Product
- SKU:
- 10-1058
- Additional Names:
- 14-3-3 protein tau
- translate.label.attr.clone:
- ABM52H6
- Clonality:
- Monoclonal
- Extra Details:
- 14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.
- Format:
- Purified
- Gene Details:
- Ywhaq
- Host:
- Rat
- Immunogen:
- Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.
- Isotype:
- Rat IgG2a, kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
