Monoclonal Antibody to c-MYC (Clone:9 E 10)
Product Sizes
25ug
£319.00
10-10013-25UG
100ug
£429.00
10-10013-100UG
About this Product
- SKU:
- 10-10013
- Additional Names:
- MYC||BHLHE39
- translate.label.attr.clone:
- 9 E 10
- Clonality:
- Monoclonal
- Extra Details:
- c-Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The Myc protein activates transcription as part of a heteromeric complex with Max. Myc protein represses the expression of Ferritin-H, which sequesters intracellular iron, and stimulates the expression of IRP2 (Iron Regulatory Protein-2), which increases the intracellular iron pool. Myc induces transcription of the E2F1, E2F2 and E2F3 genes. Myc-induced S phase and apoptosis requires distinct E2F activities. The induction of specific E2F activities is an essential component in the Myc pathways that control cell proliferation and cell fate decisions.
- Format:
- Purified
- Gene Details:
- MYC
- Host:
- Mouse
- Immunogen:
- A synthetic peptide corresponding to amino acids 408-432 (AEEQKLISEEDLLRKRREQLKHKLE) of human c-Myc was used as the immunogen for this antibody.
- Isotype:
- Mouse IgG1 Kappa
- Purification:
- Protein G Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
