In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1)
Product Sizes
1 mg
£225.00
YR0292-1MG
5 mg
£399.00
YR0292-5MG
25 mg
£1234.00
YR0292-25MG
About this Product
- SKU:
- YR0292
- Application:
- Cell-based/Functional Assay, Flow Cytometry, Immunohistochemistry
- Clonality:
- Monoclonal
- Extra Details:
- The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mouse PD-1 protein (CD279 or programmed death-1) encoded by the mouse pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD 1 antibody and the anti-mouse PD L1 antibody which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The RMP1-14 antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein.
- Formulation:
- Purified from cell culture supernatant in an animal-free facility
- Immunogen:
- mouse PD-1-transfected BHK cells
- Isotype:
- IgG2a, kappa
- Molecular Weight:
- 150kDa
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Biosimilar Antibody
- Manufacturer's Data Sheet:YR0292
