Human Integrin alpha 4 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Product Sizes
5 mg
£1617.00
YR0129-5MG
20 mg
£3183.00
YR0129-20MG
About this Product
- SKU:
- YR0129
- Additional Names:
- CD49D|IA4|ITGA4
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
- Clonality:
- Monoclonal
- Extra Details:
- Natalizumab is a monoclonal anti-integrin antibody which binds to the alpha 4 subunit of integrins to prevent migration of immune cells, and is used to treat Crohn's disease or multiple sclerosis.Humanized IgG4k monoclonal antibody produced in murine myeloma cells. Natalizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to a4-integrin.Binds to the A Alpha4-subunit of A Alpha4b 1 and A Alpha4b 7 integrins expressed on the surface of all leukocytes except neutrophils, and inhibits the A Alpha4-mediated adhesion of leukocytes to their counter-receptor(s).
- Formulation:
- Purified from cell culture supernatant in an animal-free facility
- Immunogen:
- Human Integrin alpha 4
- Isotype:
- IgG4, kappa
- Molecular Weight:
- 150 kDa
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Antibody: Biosimilar Antibody
- Manufacturer's Data Sheet:YR0129
