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Antibodies

Human CD22 Monoclonal Antibody

Product Sizes
1 mg
£486.00
YR0113-1MG
5 mg
£1355.00
YR0113-5MG
20 mg
£3531.00
YR0113-20MG
About this Product
SKU:
YR0113
Additional Names:
SIGLEC-2|SIGLEC2
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
Clonality:
Monoclonal
Extra Details:
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).
Formulation:
Purified from cell culture supernatant in an animal-free facility
Immunogen:
Human CD22
Isotype:
IgG1, kappa
Molecular Weight:
150 kDa
Purity:
>95%
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:YR0113