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Antibodies

Human IL-6R Monoclonal Antibody

Product Sizes
1 mg
£355.00
YR0003-1MG
5 mg
£885.00
YR0003-5MG
20 mg
£1721.00
YR0003-20MG
About this Product
SKU:
YR0003
Additional Names:
CD126|gp80|HIES5|IL-1Ra|IL-6R|IL-6R-1|IL-6RA|IL6Q|IL6QTL|IL6RA|IL6RQ
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
Clonality:
Monoclonal
Extra Details:
What is tocilizumab biosimilar research grade? Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, fibroblasts. IL-6 rapidly induces C-reactive protein, serum amyloid A, fibrinogen, haptoglobin, and A Alpha-1-antichymotrypsin while inhibiting production of fibronectin, albumin, and transferrin. IL-6 also induces antibody production, induces cytotoxic T-cell differentiation, and inhibits regulatory T-cell differentiation. Tocilizumab binds soluble and membrane bound IL-6 receptors, preventing IL-6 mediated inflammation.
Formulation:
Purified from cell culture supernatant in an animal-free facility
Immunogen:
Human IL-6R
Isotype:
IgG1, kappa
Molecular Weight:
150 kDa
Purity:
>95%
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:YR0003