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Proteins and Peptides

Recombinant Human Asparaginyl endopeptidase/Legumain/LGMN Protein

Product Sizes
50 ug
£540.00
RP03221LQ-50UG
About this Product
SKU:
RP03221LQ
Additional Names:
Asparaginyl Endopeptidase|Legumain|LGMN|Protease Cysteine 1|PRSC1
Extra Details:
Legumain is a lysosomal cysteine protease which is a member of the peptidase C13 family. Though it is found in many tissues, it is highly expressed in the kidney, heart, and placenta. Legumain has a strict specificity for hydrolysis of asparaginyl bonds and can also cleave aspartyl bonds slowly, especially under acidic conditions. Over-expression Legumain in tumors is significant for invasion and metastasis. In addition, Legumain may be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system and negative regulation of neuron apoptosis.
Formulation:
Recombinant Human Asparaginyl endopeptidase/Legumain/LGMN Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Ile18-Tyr433) of Human Asparaginyl endopept
Immunogen:
Ile18-Tyr433
Molecular Weight:
55-60 kDa
Purity:
≥95%
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes