Recombinant Human Insulysin/IDE Protein
Product Sizes
50 ug
£540.00
RP03201LQ-50UG
About this Product
- SKU:
- RP03201LQ
- Additional Names:
- Abeta-Degrading Protease|IDE|Insulin Protease|Insulin-Degrading Enzyme|Insulinase|Insulysin
- Extra Details:
- Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid B Beta-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF A Alpha and B Beta-endorphin.
- Formulation:
- Recombinant Human Insulysin/IDE Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Met42-Leu1019) of Human Insulysin/IDE (Accession #P14735) fused with
- Immunogen:
- Met42-Leu1019
- Molecular Weight:
- 120 kDa
- Purity:
- ≥95%
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:RP03201LQ
