Recombinant Human Calmodulin-1/CALM1 Protein
Product Sizes
10 ug
£145.00
RP02931-10UG
50 ug
£288.00
RP02931-50UG
500 ug
£1478.00
RP02931-500UG
1000 ug
£1954.00
RP02931-1000UG
About this Product
- SKU:
- RP02931
- Additional Names:
- CALM1,CALML2,CAMI,CPVT4,DD132,LQT14,PHKD,caM, CAMI, CPVT4, DD132, LQT14, PHKD, caM
- Extra Details:
- Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.
- Formulation:
- Recombinant Human Calmodulin-1/CALM1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Lys149) of human Calmodulin-1/CALM1 (Accession #NP_001316851.
- Immunogen:
- Met1-Lys149
- Molecular Weight:
- 16 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Sequence:
- MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP02931
