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Proteins and Peptides

Recombinant Human beta Defensin 3/DEFB103A Protein

Product Sizes
100 ug
£621.00
RP02867-100UG
About this Product
SKU:
RP02867
Additional Names:
BD-3|Beta-defensin 3|DEFB-3|DEFB103A|hBD-3|HBD3
Extra Details:
Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. It is also expressed in salivary gland, bone marrow, colon, stomach, polyp and larynx. However, in small intestine, it cannot be detected. Defensin has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. Beta-defensin 3 kills multiresistant S.aureus and vancomycin-resistent E.faecium. It has no significant hemolytic activity.
Formulation:
Recombinant Human beta Defensin 3/DEFB103A Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gly23-Lys67) of human beta Defensin 3/DEFB103A (Accession #N
Immunogen:
Gly23-Lys67
Molecular Weight:
12 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins