Recombinant Cynomolgus LILRA4/ILT-7/CD85g Protein
Product Sizes
100 ug
£353.00
RP02681-100UG
500 ug
£1336.00
RP02681-500UG
1000 ug
£1954.00
RP02681-1000UG
About this Product
- SKU:
- RP02681
- Additional Names:
- CD85g|ILT-7|ILT7|ILT7MGC129598|LILRA4|MGC129597
- Extra Details:
- LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
- Formulation:
- Recombinant Cynomolgus LILRA4/ILT-7/CD85g Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu24-Asn446) of Cynomolgus LILRA4/ILT-7/CD85g (Accessio
- Immunogen:
- Glu24-Asn446
- Molecular Weight:
- 58-68 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP02681
