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Proteins and Peptides

Recombinant Mouse LAIR-1/CD305 Protein

Product Sizes
100 ug
£ POA
RP02669-100UG
500 ug
£1413.00
RP02669-500UG
1000 ug
£1764.00
RP02669-1000UG
About this Product
SKU:
RP02669
Additional Names:
CD305|HLAIR1|LAIR-1|LAIR1
Extra Details:
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.
Formulation:
Recombinant Mouse LAIR-1/CD305 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln22-Tyr141) of mouse LAIR-1/CD305 (Accession #Q8BG84-1) fused wit
Immunogen:
Gln22-Tyr141
Molecular Weight:
30-42 kDa
Purity:
≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
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