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Proteins and Peptides

Biotinylated Recombinant Human PDGFR-beta/CD140b Protein

Product Sizes
100 ug
£657.00
RP02478B-100UG
500 ug
£2555.00
RP02478B-500UG
About this Product
SKU:
RP02478B
Additional Names:
CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR-1,PDGFR1,PENTT,PDGF Receptor beta,PDGFRB,PDGFR beta
Conjugate:
Biotin
Extra Details:
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
Formulation:
Biotinylated Recombinant Human PDGF R beta Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Leu33-Phe530) of Human PDGF R beta fused with His tag and Av
Immunogen:
Leu33-Phe530
Molecular Weight:
78-115 kDa
Physical State:
Lyophilized
Purity:
≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes