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Proteins and Peptides

Recombinant Mouse Alkaline phosphatase,tissue-nonspecific isozyme/ALPL Protein

Product Sizes
10 ug
£145.00
RP01999-10UG
20 ug
£193.00
RP01999-20UG
50 ug
£288.00
RP01999-50UG
100 ug
£431.00
RP01999-100UG
500 ug
£1240.00
RP01999-500UG
1000 ug
£1954.00
RP01999-1000UG
About this Product
SKU:
RP01999
Additional Names:
Alpl, Akp-2, Akp2,Alkaline phosphatase, tissue-nonspecific isozyme, AP-TNAP, TNAP, TNSALP, EC:3.1.3.1, Alkaline phosphatase 2, Alkaline phosphatase liver/bone/kidney isozyme, Phosphoamidase, Phosphocreatine phosphatase, EC:3.9.1.1
Extra Details:
Several distinct genes encode alkaline phosphatases (APs) in mice with different tissue-specific expression patterns. The Alpl gene, also known as Akp2, encodes the liver/bone/kidney isozyme, also known as the tissue-nonspecific AP (TNAP). The Alpl gene is a key regulator of bone mineralization in mice . A variety of mutations in the human ALPL gene leads to different forms of hypophosphatasia, characterized by poorly mineralized cartilage and bones . The native ALPL is a glycosylated homodimer attached to the membrane through a GPI-anchor.
Formulation:
Recombinant Mouse Alkaline phosphatase,tissue-nonspecific isozyme/ALPL Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe18-Ala500) of Mouse Alka
Immunogen:
Phe18-Ala500
Molecular Weight:
66 -75kDa
Physical State:
Lyophilized
Purity:
≥90%
Sequence:
FVPEKERDPSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNLKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGKAGAMTSQKDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWA
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes