Recombinant Human IFN-alpha 10 Protein
Product Sizes
10 ug
£133.00
RP01919-10UG
20 ug
£181.00
RP01919-20UG
50 ug
£240.00
RP01919-50UG
100 ug
£353.00
RP01919-100UG
500 ug
£1002.00
RP01919-500UG
1000 ug
£1574.00
RP01919-1000UG
About this Product
- SKU:
- RP01919
- Additional Names:
- IFN-alpha 10|IFN-alpha C|IFN-alpha-10|IFN-alphaC|IFNA10|IFNalpha C|interferon alpha-10|Interferon alpha-6L|Interferon alpha-C|interferon, alpha 10|LeIF C|MGC119878|MGC119879
- Extra Details:
- Interferons (IFN) are a family of cytokines with potent antiviral, antiproliferative and immunomodulatory properties, classified based on their binding specificity to cell surface receptors . Human IFNA2 was originally cloned in the early '80s and now more than a dozen closely related IFN alpha subtypes have been identified in both the human and mouse genome, each sharing about 80% amino acid (aa) sequence homology. Structurally, type I IFNs belong to the class of five helicalbundle cytokines, with the IFNA subtypes containing 2 conserved disulfide bonds. Mature human IFNA10 shares 61% aa sequence identity with mouse IFNA7. The type I IFNs bind to the interferon alpha receptor (IFNAR), which consists of two subunits: IFNAR1 (alpha -subunit) and IFNAR2 (beta -subunit). Individual IFNA subtypes are known to display unique efficacies to viral protection, and IFNA10 has been shown to be a strong inducer of IFN-stimulated genes and antiviral protection. Additionally, IFNA10 exhibits weak antiviral effects against SARS-CoV-2 .
- Formulation:
- Recombinant Human IFN-alpha 10 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human IFN-alpha 10/IFNA10 (Accession #NP_002162.1)
- Immunogen:
- Cys24-Asp189
- Molecular Weight:
- 20-25 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥90%
- Sequence:
- CDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFRIPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP01919
