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Proteins and Peptides

Recombinant Mouse MYDGF Protein

Product Sizes
10 ug
£163.00
RP01822-10UG
20 ug
£223.00
RP01822-20UG
50 ug
£336.00
RP01822-50UG
100 ug
£508.00
RP01822-100UG
500 ug
£1478.00
RP01822-500UG
1000 ug
£2335.00
RP01822-1000UG
About this Product
SKU:
RP01822
Additional Names:
Mydgf,Myeloid-derived growth factor, MYDGF
Extra Details:
Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair.
Formulation:
Recombinant Mouse MYDGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val25-Leu166) of mouse MYDGF (Accession #NP_543027.1) fused with a 6xHis t
Immunogen:
Val25-Leu166
Molecular Weight:
15-25 kDa
Physical State:
Lyophilized
Purity:
≥95%
Sequence:
VSEPTTVPFDVRPGGVVHSFSQDVGPGNKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTIWRPQGKSYLYFTQFKAELRGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTAVSHRPGAFKAELSKLVIVAKAARSEL
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins