Recombinant Rat IL-21 Protein
Product Sizes
10 ug
£163.00
RP01756-10UG
20 ug
£223.00
RP01756-20UG
50 ug
£336.00
RP01756-50UG
100 ug
£508.00
RP01756-100UG
500 ug
£1478.00
RP01756-500UG
1000 ug
£2335.00
RP01756-1000UG
About this Product
- SKU:
- RP01756
- Additional Names:
- CVID11|IL-21|Za11
- Extra Details:
- IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).
- Formulation:
- Recombinant Rat IL-21 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His18-Ser146) of rat IL-21 (Accession #NP_001102413.1) fused with a 6xHis ta
- Immunogen:
- His18-Ser146
- Molecular Weight:
- 15-35 kDa
- Physical State:
- Lyophilized
- Purity:
- ≥90%
- Sequence:
- HKSSPQRPDHLLIRLRHLMDIVEQLKIYENDLDPELLTAPQDVKGQCEHEAFACFQKAKLKPSNTGNNKTFINDLLAQLRRRLPAKRTGNKQRHMAKCPSCDLYEKKTPKEFLERLKWLLQKMIHQHLS
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ABclonal Technology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:RP01756
