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Proteins and Peptides

Recombinant human Trk-A/NTRK1 Protein

Product Sizes
10 ug
£133.00
RP01726-10UG
20 ug
£181.00
RP01726-20UG
50 ug
£240.00
RP01726-50UG
100 ug
£353.00
RP01726-100UG
500 ug
£1002.00
RP01726-500UG
1000 ug
£1574.00
RP01726-1000UG
About this Product
SKU:
RP01726
Additional Names:
MTC|NTRK1|p140-TrkA|TRK|Trk-A|TRK1|TRKA
Extra Details:
This protein is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Formulation:
Recombinant human Trk-A/NTRK1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala33-Glu413) of human Trk-A/NTRK1 (Accession #NP_001012331.1) fused
Immunogen:
Ala33-Glu413
Molecular Weight:
60-100 kDa
Physical State:
Lyophilized
Purity:
≥90%
Sequence:
AAPCPDACCPHGSSGLRCTRDGALDSLHHLPGAENLTELYIENQQHLQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNLSFNALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSGDPVEKKDE
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes